Tybulewicz, V. L. J.: search on Z-Library

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1

The SYK tyrosine kinase: a crucial player in diverse biological functions

Mócsai, Attila, Ruland, Jürgen, Tybulewicz, Victor L. J.

Journal:

Nature Reviews Immunology

Year:

2010

Language:

english

File:

PDF, 1.70 MB

english, 2010

2

Using primary neurons from transgenic mice to identify genes on human chromosome 21 influencing Alzheimer's neuropathology

Choong, Xun Yu, Raha, Alex, Tybulewicz, Victor, Wiseman, Frances, Fisher, Elizabeth

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

3

Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years

Hithersay, Rosalyn, Startin, Carla M., Hamburg, Sarah, Mok, Kin Y., Hardy, John, Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Nizetic, Dean, Strydom, André

Journal:

Year:

2018

Language:

english

File:

PDF, 351 KB

english, 2018

4

Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21

Aarti Ruparelia, Frances Wiseman, Olivia Sheppard, Victor L.J. Tybulewicz, Elizabeth M.C. Fisher

Journal:

Journal of Biomedical Research

Year:

2010

Language:

english

File:

PDF, 649 KB

english, 2010

5

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

Turner, Martin, Joseph Mee, P., Costello, Patrick S., Williams, Owen, Price, Abigail A., Duddy, Linda P., Furlong, Michael T., Geahlen, Robert L., Tybulewicz, Victor L. J.

Journal:

Year:

1995

File:

PDF, 1.08 MB

1995

6

Vav-family proteins in T-cell signalling

Victor LJ Tybulewicz

Journal:

Current Opinion in Immunology

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

7

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

Wiseman, Frances K., Al-Janabi, Tamara, Hardy, John, Karmiloff-Smith, Annette, Nizetic, Dean, Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Strydom, André

Journal:

Nature Reviews Neuroscience

Year:

2015

Language:

english

File:

PDF, 429 KB

english, 2015

8

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model

Afua Mensah, Claire Mulligan, Jackie Linehan, Sandra Ruf, Aideen O'Doherty, Beata Grygalewicz, Janet Shipley, Juergen Groet, Victor Tybulewicz, Elizabeth Fisher, Sebastian Brandner, Dean Nizetic

Journal:

BMC Developmental Biology

Year:

2007

Language:

english

File:

PDF, 971 KB

english, 2007

9

Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain

Jon O. Cleary, Frances K. Wiseman, Francesca C. Norris, Anthony N. Price, ManKin Choy, Victor L.J. Tybulewicz, Roger J. Ordidge, Sebastian Brandner, Elizabeth M.C. Fisher, Mark F. Lythgoe

Journal:

Year:

2011

Language:

english

File:

PDF, 2.29 MB

english, 2011

10

Signalling through the TCR

D. Cantrell, J. Bluestone, E. Vivier, V. Tybulewicz

Journal:

Research in Immunology

Year:

1998

Language:

english

File:

PDF, 233 KB

english, 1998

11

Themis2 Is Not Required for B Cell Development, Activation, and Antibody Responses

Hartweger, H., Schweighoffer, E., Davidson, S., Peirce, M. J., Wack, A., Tybulewicz, V. L. J.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 2.84 MB

english, 2014

12

Requirement for Rac1 in a K-ras Induced Lung Cancer in the Mouse

Kissil, J. L., Walmsley, M. J., Hanlon, L., Haigis, K. M., Bender Kim, C. F., Sweet-Cordero, A., Eckman, M. S., Tuveson, D. A., Capobianco, A. J., Tybulewicz, V. L.J., Jacks, T.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 906 KB

english, 2007

13

Hyaluronic Acid Predicts Hepatic Fibrosis in Children With Hepatic Disease

Hartley, Jane L., Brown, Rachel M., Tybulewicz, Aniela, Hayes, Peter, Wilson, David C., Gillett, Peter, McKiernan, Patrick

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2006

Language:

english

File:

PDF, 110 KB

english, 2006

14

The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells

Josephine Meade, Victor L. J. Tybulewicz, Martin Turner

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

15

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

Connor, Frances, Bertwistle, David, Mee, P. Joseph, Ross, Gillian M., Swift, Sally, Grigorieva, Elena, Tybulewicz, Victor L. J., Ashworth, Alan

Journal:

Nature Genetics

Year:

1997

File:

PDF, 1.01 MB

1997

16

Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases

Colucci, Francesco, Schweighoffer, Edina, Tomasello, Elena, Turner, Martin, Ortaldo, John R., Vivier, Eric, Tybulewicz, Victor L. J., Di Santo, James P.

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 1.19 MB

english, 2002

17

Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin

Maria da Glória Sousa, Delyth M. Reid, Edina Schweighoffer, Victor Tybulewicz, Jürgen Ruland, Jean Langhorne, Sho Yamasaki, Philip R. Taylor, Sandro R. Almeida, Gordon D. Brown

Journal:

Cell Host & Microbe

Year:

2011

Language:

english

File:

PDF, 377 KB

english, 2011

18

Vav1 GEF activity is required for T cell mediated allograft rejection

Dirk Haubert, Jianping Li, Alexander Saveliev, Thomas Calzascia, Esther Sutter, Barbara Metzler, Daniel Kaiser, Victor L.J. Tybulewicz, Gisbert Weckbecker

Journal:

Transplant Immunology

Year:

2012

Language:

english

File:

PDF, 1.54 MB

english, 2012

19

Syk, c-Src, the αvβ3 Integrin, and ITAM Immunoreceptors, in Concert, Regulate Osteoclastic Bone Resorption

Wei Zou, Hideki Kitaura, Jennifer Reeve, Fanxin Long, Victor L. J. Tybulewicz, Sanford J. Shattil, Mark H. Ginsberg, F. Patrick Ross and Steven L. Teitelbaum

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 3.13 MB

english, 2007

20

Signalling for B cell survival

Schweighoffer, Edina, Tybulewicz, Victor LJ

Journal:

Current Opinion in Cell Biology

Year:

2018

Language:

english

File:

PDF, 858 KB

english, 2018

21

Defective immunoglobulin class switching in Vav-deficient mice is attributable to compromised T cell help

Adam Gulbranson-Judge, Victor L. J. Tybulewicz, Alice E. Walters, Kai-Michael Toellner, Ian C. M. MacLennan, Martin Turner

Journal:

European Journal of Immunology

Year:

1999

Language:

english

File:

PDF, 241 KB

english, 1999

22

Chemokines and the immunological synapse

Victor L. J. Tybulewicz

Journal:

Year:

2002

Language:

english

File:

PDF, 37 KB

english, 2002

23

10.1038/79808

Gomez, Manuel, Tybulewicz, Victor, Cantrell, Doreen A.

Journal:

Nature Immunology

Year:

2000

Language:

english

File:

PDF, 182 KB

english, 2000

24

Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins

Neil C. Rogers, Emma C. Slack, Alexander D. Edwards, Martijn A. Nolte, Oliver Schulz, Edina Schweighoffer, David L. Williams, Siamon Gordon, Victor L. Tybulewicz, Gordon D. Brown, Caetano Reis e Sousa

Journal:

Year:

2005

Language:

english

File:

PDF, 620 KB

english, 2005

25

Rac1 Is Essential for Platelet Lamellipodia Formation and Aggregate Stability under Flow

McCarty, O. J. T., Larson, M. K., Auger, J. M., Kalia, N., Atkinson, B. T., Pearce, A. C., Ruf, S., Henderson, R. B., Tybulewicz, V. L. J., Machesky, L. M., Watson, S. P.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 610 KB

english, 2005

26

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

Victor L.J. Tybulewicz, Camila E. Crawford, Peter K. Jackson, Roderick T. Bronson, Richard C. Mulligan

Journal:

Year:

1991

Language:

english

File:

PDF, 2.28 MB

english, 1991

27

Quantitative Proteomics Characterization of a Mouse Embryonic Stem Cell Model of Down Syndrome

Wang, Y., Mulligan, C., Denyer, G., Delom, F., Dagna-Bricarelli, F., Tybulewicz, V. L. J., Fisher, E. M. C., Griffiths, W. J., Nizetic, D., Groet, J.

Journal:

Molecular & Cellular Proteomics

Year:

2009

Language:

english

File:

PDF, 536 KB

english, 2009

28

Syk, c-Src, the v 3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

Zou, W., Kitaura, H., Reeve, J., Long, F., Tybulewicz, V. L.J., Shattil, S. J., Ginsberg, M. H., Ross, F. P., Teitelbaum, S. L.

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 2.10 MB

english, 2007

29

HYALURONIC ACID AS A NON-INVASIVE PREDICTOR OF FIBROSIS IN PAEDIATRIC LIVER DISEASE

Hartley, JL, Brown, RM, Tybulewicz, A, Hayes, P, Wilson, D, Gillett, P, McKiernan, P

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2005

Language:

english

File:

PDF, 1.06 MB

english, 2005

30

Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene

Tybulewicz, V. L. J., Tremblay, M. L., LaMarca,, Willemsen, R., Stubblefield, B. K., Winfield, S., Zablocka, B., Sidransky, E., Martin, B. M., Huang, S. P.

Journal:

Year:

1992

File:

PDF, 643 KB

1992

31

Syk and Slp-76 Mutant Mice Reveal a Cell-Autonomous Hematopoietic Cell Contribution to Vascular Development

Eric Sebzda, Chris Hibbard, Shawn Sweeney, Farhad Abtahian, Natalie Bezman, Gina Clemens, Jonathan S. Maltzman, Lan Cheng, Feiyan Liu, Martin Turner, Victor Tybulewicz, Gary A. Koretzky, Mark L. Kahn

Journal:

Developmental Cell

Year:

2006

Language:

english

File:

PDF, 847 KB

english, 2006

32

A Key Regulatory Role for Vav1 in Controlling Lipopolysaccharide Endotoxemia via Macrophage-Derived IL-6

Zenker, S., Panteleev-Ivlev, J., Wirtz, S., Kishimoto, T., Waldner, M. J., Ksionda, O., Tybulewicz, V. L. J., Neurath, M. F., Atreya, I.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

33

Distinct Roles for the Linker Region Tyrosines of Syk in FcϵRI Signaling in Primary Mast Cells

Simon, Maria, Vanes, Lesley, Geahlen, Robert L., Tybulewicz, Victor L. J.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 891 KB

english, 2005

34

Preterm meconium staining of the amniotic fluid: associated findings and risk of adverse clinical outcome

Tybulewicz, A T

Journal:

Archives of Disease in Childhood - Fetal and Neonatal Edition

Year:

2004

Language:

english

File:

PDF, 58 KB

english, 2004

35

Cutting Edge: Rac GTPases Sensitize Activated T Cells to Die via Fas

Ramaswamy, M., Dumont, C., Cruz, A. C., Muppidi, J. R., Gomez, T. S., Billadeau, D. D., Tybulewicz, V. L. J., Siegel, R. M.

Journal:

The Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 542 KB

english, 2007

36

T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue

David, R., Ma, L., Ivetic, A., Takesono, A., Ridley, A. J., Chai, J.-G., Tybulewicz, V. L., Marelli-Berg, F. M.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.88 MB

english, 2009

37

A biochemical and ultrastructural evaluation of the type 2 Gaucher mouse

R. Willemsen, V. Tybulewicz, E. Sidransky, W. K. Eliason, B. M. Martin, M. E. LaMarca, A. J. J. Reuser, M. Tremblay, H. Westphal, R. C. Mulligan, E. I. Ginns

Journal:

Molecular and Chemical Neuropathology (Neurochemical Pathology)

Year:

1995

Language:

english

File:

PDF, 2.32 MB

english, 1995

38

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization

Claire M. Wells, Parag J. Bhavsar, Iwan R. Evans, Elena Vigorito, Martin Turner, Victor Tybulewicz, Anne J. Ridley

Journal:

Experimental Cell Research

Year:

2005

Language:

english

File:

PDF, 373 KB

english, 2005

39

The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway

Schweighoffer, Edina, Vanes, Lesley, Nys, Josquin, Cantrell, Doreen, McCleary, Scott, Smithers, Nicholas, Tybulewicz, Victor L.J.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.39 MB

english, 2013

40

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

Hara, Hideki, Tsuchiya, Kohsuke, Kawamura, Ikuo, Fang, Rendong, Hernandez-Cuellar, Eduardo, Shen, Yanna, Mizuguchi, Junichiro, Schweighoffer, Edina, Tybulewicz, Victor, Mitsuyama, Masao

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

41

A New Look at Syk in and T Cell Development Using Chimeric Mice with a Low Competitive Hematopoietic Environment

Colucci, F., Guy-Grand, D., Wilson, A., Turner, M., Schweighoffer, E., Tybulewicz, V. L. J., Di Santo, J. P.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

42

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.

Karaplis, A C, Luz, A, Glowacki, J, Bronson, R T, Tybulewicz, V L, Kronenberg, H M, Mulligan, R C

Journal:

Genes & Development

Year:

1994

Language:

english

File:

PDF, 2.85 MB

english, 1994

43

1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

Nodari, A., Zambroni, D., Quattrini, A., Court, F. A., D'Urso, A., Recchia, A., Tybulewicz, V. L.J., Wrabetz, L., Feltri, M. L.

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 7.14 MB

english, 2007

44

A Critical Role for Syk in Signal Transduction and Phagocytosis Mediated by Fc Receptors on Macrophages

Crowley, M. T., Costello, P. S., Fitzer-Attas, C. J., Turner, M., Meng, F., Lowell, C., Tybulewicz, V. L. J., DeFranco, A. L.

Journal:

Journal of Experimental Medicine

Year:

1997

Language:

english

File:

PDF, 546 KB

english, 1997

45

Rac1-Dependent Cell Cycle Exit of MGE Precursors and GABAergic Interneuron Migration to the Cortex

Vidaki, M., Tivodar, S., Doulgeraki, K., Tybulewicz, V., Kessaris, N., Pachnis, V., Karagogeos, D.

Journal:

Cerebral Cortex

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

46

Vav1 transduces TCR signals modulating lymphocyte adhesion and morphology

Tybulewicz, V.L.J., Ardouin, L., Reynolds, L., Kioussis, D.

Journal:

Biochemical Society Transactions

Year:

2001

Language:

english

File:

PDF, 89 KB

english, 2001

47

Inefficient clustering of tyrosine-phosphorylated proteins at the immunological synapse in response to an antagonist peptide

Lesley A. Smyth, Laurence Ardouin, Owen Williams, Trisha Norton, Victor Tybulewicz, Dimitris Kioussis

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 241 KB

english, 2002

48

Tyrosine kinase SYK: essential functions for immunoreceptor signalling

Martin Turner, Edina Schweighoffer, Francesco Colucci, James P Di Santo, Victor L Tybulewicz

Journal:

Immunology Today

Year:

2000

Language:

english

File:

PDF, 213 KB

english, 2000

49

Lymphocyte signaling: beyond knockouts

Saveliev, Alexander, Tybulewicz, Victor L J

Journal:

Nature Immunology

Year:

2009

Language:

english

File:

PDF, 420 KB

english, 2009

50

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

LeibundGut-Landmann, Salomé, Groß, Olaf, Robinson, Matthew J, Osorio, Fabiola, Slack, Emma C, Tsoni, S Vicky, Schweighoffer, Edina, Tybulewicz, Victor, Brown, Gordon D, Ruland, Jürgen

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 335 KB

english, 2007

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